Original Article
Nishat Akther, Farjana Akter Hira, Ayesha Khatun, Md. Shawon, Shaike M. Abdullah , Esrat Jahan Shorna, Ashekul Islam, Khairul Islam, Nazmul Md Hossain
J Adv Biotechnol Exp Ther. 2023; 6(2): 419-428.

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ABSTRACT
Antimicrobial resistance has become an alarming issue all over the world. Moreover, in the developing countries as well as in Bangladesh facing this badly due to lack of study. Antibiotic resistance is prevalent among the bacterial pathogens causing urinary tract infections. Urinary tract infections affect >30% of people around the world. Worldwide, about 150 million people experience urinary tract infections each year. Antimicrobial treatment is often prescribed ‘empirically’ without antibiotic susceptibility testing to treat urinary tract infections (UTIs). The prevalence of antibiotic resistance is worsening, probably because of the increasing number of multidrug-resistant bacterial strains and the indiscriminate use of broad-spectrum antibiotics and empirical treatment. This study aims to determine the frequency and antibiotic resistance pattern of bacteria from suspected UTIs in Bangladeshi patients. In our study, about 200 samples of positive UTIs patients were analyzed with several parameters to see the antibiotic resistance rate. After examining the patient’s sample of UTIs antibiotic resistance rate is alarming and the most causative bacteria is Escherichia coli which is about 61.8%. Among the 200-urine sample suspected UTI patients 66% and 30% are female and male, respectively. Empirical therapy should be guided to control the antibiotic resistance. Especially, developing country should accept the challenge with proper infrastructure to get the surveillance of resistance, as resistance varies from region to region. Appropriate antibiotics should be focused for the rational use of antibiotics to prevent antibiotics resistance through common infections.

KEYWORDS
Antibiotic resistance, Antibiotics, Escherichia coli, Urinary tract infection, Uropathogens.